Audible Manger 5.1 is now running a lot better with CX 6.0. All the buttons and menus work, and the fonts are much cleaner. It can also successfully active to play audible content. As with most Wine apps hardware access does not work. So no CD burning, and I doubt any of the players will be able to connect to it. It also does not remember where it left off when playing a book so you have to fast forward it to the point you left off. The download helper app also usually closes by it self but the apps are still running and have to be killed manually. You also can not download more than one book at a time.
Since the folder changes the command to use the download helper has changed a little bit.
/opt/cxoffice/bin/wine --start "/home/<<Your_User_ID>>/.cxoffice/Win2k-Audible/drive_c/Program Files/Audible/Bin/AudibleDownloadHelper.exe"
Since Audible apps are not supported it is a good idea to install them in their own 2k based bottle. I created a bottle called "Win2k-Audible". If you do this as well you will need to add --bottle <<Bottle_Name>> to the comand. So for me it was :
/opt/cxoffice/bin/wine --bottle "Win2k-Audible" --start "/home/<<Your_User_ID>>/.cxoffice/Win2k-Audible/drive_c/Program Files/Audible/Bin/AudibleDownloadHelper.exe"