Machine used here is a 2010 11.6" MacBook Air running CX 14.0.3 on OS X 10.10.1. The game (installed from the physical "black stripe" GOTY release) works almost perfectly; the only hitch is that graphical options can't be changed in game or else the game itself will crash. Setting resolution and color depth via the registry (as posted in the Tips & Tricks section), however, does work.
Other than that, in-game movies, saving, and loading all work without any problems.