In theory yes. A crossover bottle is a simple wine prefix, so you can make Wine use a crossover bottle by setting the WINEPREFIX environment variable, e.g.:
WINEPREFIX=~/.cxoffice/mybottle wine foo.exe
However, CrossOver has a few registry settings and DLL overrides that can break Wine, and Wine may try to update some registry settings that may break some apps in CrossOver, so use this at your own risk. You can also share just the C drive(not the registry) by changing the dosdevices/c: symlink in .wine or the bottle
Please Note: This Forum is for non-application specific questions relating to installation/configuration of CrossOver. All application-specific posts to this Forum will be moved to their appropriate Compatibility Center Forum.
CrossOver Forums: the place to discuss running Windows applications on Mac and Linux
We're rebels. We're misfits. But mostly, we're software liberators. And we're very, very good at what we do. We have to be. Lots of developers work with open source, but only a tiny fraction of those are good enough to get software that was designed for one platform to work on another one. We invented CrossOver software - a unique approach to cross-platform compatibility that does not require dual-boot or another OS license. We launched PortJump to help app and game developers broaden their market beyond Windows® users. And we launched ExecMode to help organizations solve really ugly technical challenges.