We actively test and support the most recent releases from the major Linux distributions,
Red Hat Enterprise Linux
We test the 64-bit (and when possible 32-bit) build of the above distributions. We test the Unity, Gnome, and KDE desktop environments.
You should be able to run CrossOver on a variety of other distributions, particularly distributions based on those listed above. However, we do not test or support other distributions and so we cannot guarantee Crossover will work.