I'm in the early stages of testing this application but so far it's working very well.
I'm on crossover games 7.1
created a win98 bottle, installed Exile and Quicktime 6.x (which was on the DVD of the game) and did a minimal (requires DVD) install.
I used the Ubisoft DVD (Myst Anniversary Edition).
With the exception of occasional mouse trails being left painted at the bottom of the screen until I move the camera I haven't noticed anything wrong.